Stretch-induced Fetal Type II Cell Differentiation Is Mediated via ErbB1-ErbB4 Interactions
نویسندگان
چکیده
منابع مشابه
1 Stretch - induced fetal type II cell differentiation is mediated via ErbB 1 - ErbB 4 interactions
Background: Mechanical forces and ErbB receptors are critical for fetal lung development. Results: Deletion of ErbB1 or downregulation or ErbB4 prevented stretchinduced type II cell differentiation via ERK. Conclusion: Interactions between ErbB1 and ErbB4 are critical for stretch-induced type II cell differentiation. Significance: Learning how mechanical signal regulate fetal lung development i...
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Juan Sanchez-Esteban, Yulian Wang, Edward J. Filardo, Lewis P. Rubin, and Donald E. Ingber Division of Neonatology, Department of Pediatrics, Women and Infants Hospital of Rhode Island; Division of Hematology and Oncology, Department of Medicine, Rhode Island Hospital, Brown Medical School, Providence, Rhode Island; and Vascular Biology Program, Departments of Pathology and Surgery, Children’s ...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2012
ISSN: 0021-9258
DOI: 10.1074/jbc.m111.313163